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# Yersinia pestis CO92, CO92

>YPO0034 putative membrane permease
MSTQSAELDTAPPSPAHPSELIYHLEDRPPLPQTLFAACQHLLAMFVAVI
TPGLLICQALGLPAEDTQRIISMSLFASGLASLLQIKTWGPVGSGLLSIQ
GTSFNFVSPLIMGGLALKNGGADIPTMMAALFGTLMVASCTEILLSHVLH
LARRIITPLVSGIVVMIIGLSLIQVGLTSIGGGYGAMSDNTFGAPKNLLL
AGAVLGVIILLNRQRNPYLRVASLVIAMAVGYLLAWALGMLPESRPVVDT
ALITIPTPLYYGLSFDWNLLIPLMLIFMVTSLETIGDITATSDVSEQPVR
GPLYMKRLKGGVLANGLNSMLSAIFNTFPNSCFGQNNGVIQLTGVASRYV
GFVVAIMLIILGLFPAVAGFVQHIPEPVLGGATLVMFGTIAASGVRIVSR
ETLNRRAIMIMALSLAVGMGVAQQPLILQFAPDWIKTLFSSGIAAGGITA
IVLNLLFPQEK
>YPO1611 hypothetical protein
MAEETIFSKIIRREIPADVVYQDELVTAFRDIAPQAPTHILIIPNVLIPT
VNDVTAEHEAALGRMVTVAAKLAEQEGIAEDGYRLIINCNHHAGQVVYHI
HMHLVGGRELGPLLPHK
>YPO3622 putative deoxyribose-phosphate aldolase
MIDFNDPRQVAKAIQFTNVNADLTREGVIKHLNICLEYQFDAAMIAPCWV
YLAKDVLKGSGVRVATTVNFPQANDTTAMKVAIVRELAKEGADEFDFPPN
PGFLLGGLDELYFNELKEVTHIAHDLGMKVKAMLEFGFITEEAMKIKATR
YAYEAGIDWVKQSSGWGKGGCAATVEDVQLLKANIQAPCRVKVSGKVNTL
EKMKEMFLAGAELVGTSSGPELVKGLTGDINAY
>YPO2923 putative zinc-binding protein
MRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIM
ALRQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKT
GAAGSLVDILRHPGMNHQIEVSAGILAIACSHQLSAFFRQRREQQKALKQ
AQRAAEGKF
>YPO4019 adenine phosphoribosyltransferase
MILLKNVYKNAQVVNSGKALTTVNEFTDQLPALRPAVLLEVAHKVIQIID
MDIDKIVTEEDKGAPLATAVSLLSGKPLAMARWYPYSLSELNNNVVNISS
EYFEGVVYLNGISAGDRVAIIDDTLSTGGTVIALIKAIQNSGGIVKDVIC
AVEKIQNNGKKNIFTQTGINVKTLMKISVKPHGVDIIE
>YPO0945 putative deoxyribonucleotide triphosphate pyrophosphatase
MQKIVLATGNPGKVRELANLLADFGLDVVAQTELGVESAEETGLTFIENA
ILKARHAAQTTGLPAIADDSGLAVDALGGAPGIYSARYAGTDASDQENLE
KLLVALQNVPDEKRGAQFHCVLVYMRHAEDPTPLVFHGQWPGVIAHQPAG
AAGFGYDPIFYVPALGKTAAELTREEKHAVSHRGQALKLMLDALRDA
>YPO0292 hypothetical protein
MMTTQPPVYRRELSGGTLTVIPNSSNIPLDSLFDIAERRNPKRAFLFVSK
VLGRHIPVSPATMRNVYRQLAERFPADLPGPVLFIGMAETAVGLAAGVFQ
ELRGTVAEPVFLTSTRHPVDGDLLCEFKENHSHATDHLLYLPSDPVLRAR
LQRARSVVLIDDEATTGNTFINLLQALRDANLNGLEKVVAVTLTDWSGSA
LTERCPLPVTTVSLITGEWNWSPIPDAPVPVMPACNVTARGKVAITDKQN
WGRLGMDETRADIGHKVHVLAGEKVLVLGTSEFVWQPFLLAERLEHAGAN
VKFSSITRSPIAQGHAINSIIAFSDNYGLGIPNFLYNVAHQHFDRIIVCV
ETPAESIDPTLIEQLRTVAPCVEVIAYE
>YPO1323 deoxyribose-phosphate aldolase
MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQ
QLAGSSVKVCSVIGFPLGAGLTAAKAFEAQAAINAGAQEIDMVINVGWLK
SGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVA
FVKTSTGFSTGGAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAG
ATRIGTSSGVAIVSGQQAAASGY
>YPO1296 putative Mut family protein
MSSVKPSHPLTVADVISKGVNTMSVTVGVGVIIVNQQGEVLMGKRCSQHA
PYWSIPGGHLEAGESFEQAARREVFEETGLNINEVQVVALCNNLATWREE
GKHTVSVCLLAQHLGGQPELKEPEKCQQWRWCNPRDLPEPHFEASRHSID
LWLSKRFYHPYESPVGLISNTLD
>YPO0435 putative Na+ dependent nucleoside transporter-family protein
MLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVG
RRILGGMSEGVANVIAYGNEGISFIFGGLVSDKMYEVFGGGGFVFALRVL
PVIVFFSSLIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANIFV
GQTEAPLVVRPYIATMTQSELFAVMCGGLASVAGSVLAGYAQMGVPLEYL
IAASFMAAPGGLLFAKLMVPETEQTHDKVDAIALIAEEDRPANVIDAAAS
GAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGW
VFSPIAYLIGVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELVKA
AGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGL
KAVAAGTLSNLMSATIAGFFLAL
>YPO1974 atrazine chlorohydrolase
MPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLP
GMPNLHSHAFQRMMSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVI
ARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLSQAAQDAGI
GMTLLPVLYSYAGFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQ
NQGLCFHSLRAVELSQMQQILHVSDKQLPVHIHIAEQQKEVNDCLAWCGQ
RPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLG
DGIFPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLRDQRRNRLT
CERQPAVADLLYSQALAGGRQACGRQISQLAVGYRADWLVLDGDDPYIAG
TRSASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLK
ACQQEV
>YPO2611 hypothetical protein
MNKIAQYYRELVASLTERLKNGERDIDQLVESAERRLHTVEELTRNDVEQ
IVQAVRRDLEEFARSYEESKEEFRDSVFMRVIKESLWQELADITDKTQLE
WREVFKDVSHHGVYHSGEVVGLGNLVCEKCHYHLAFYTPEVLPVCPKCGH
DQFTRRPFQP
>YPO1083 putative permease
MPNNEKISASSINPHYSPKLTNEDLAPTRKQNWGWYNIFSFWMTDVHSMG
GYVVAASFFALGLSSWQVLLSLLVGICIVQICANLVAKPSQIAGVPYAVI
CRQSFGVFGANIPAVIRGLIAVAWYGIQTYLAGNAFMLVMLKFFPSLIPL
AQSQWLGLSTLGWICFSIMWVLQAMVFWHGMNAIKRFIDFAGPAVYVVML
SLALWIVYQTGWSNISFTLASKILSPSEQVWQMLTATALVVSYFAGPLLN
FGDFSRYGKSMQEIRRGNRWGLPFNFLLFSLVTVVIVSGSQSLFGEMITD
PIETVTRVGNGVAIALGLLTMIIATIGINIVANFVSPAFDFSNCSPQRIN
FRTGGMIAAVGSVLLTPWNLFQSPIIIHYTLDVLGAFMGPLFGILIADFY
LIKRGQLYVDDLFNASSSGRYWYRGGFNPKAIMALLPAVAIGLMIIFIPN
LQQISSFSWFIGAFLGGSIYRFIARNDPLPNNAALFIRPEIGKD
>YPO3118 adk, adenylate kinase
MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKAGSELGLKAK
EIMDAGKLVTDELVIALVKERITQEDCRDGFLLDGFPRTIPQADAMKEAG
IKVDYVLEFDVPDELIVERIVGRRVHAASGRVYHVKFNPPKVEDKDDVTG
EELTIRKDDQEATVRKRLIEYHQQTAPLVSYYHKEADAGNTQYFKLDGTR
NVAEVSAELATILG
>YPO2288 amn, AMP nucleosidase
MNKLQDTGSLAVVEAIDKLEMLYDAALAALRDAISAFIRDGSLPNAAERS
KGLFSYPQLSVRWDGKFSDHHRTRAYGRFSRAGQYSTTITRPALFREYLT
EQMTLLESEYGAVFEVTPSQQEMPYPFVIDGSDLILDRSMTAGLAQHFPT
TDLAKIGDGITDGIETIALGTASLGSAVSDLPLSHFDALRTDFSLARLKH
YTGTPAEDIQPYILFTNYSRYVDEFVRWAGEQILDPNSPYKALSCAGGSY
ITAENADPEKTLSDLAWKKHQMPAYHLIAKNGQGITLVNIGVGPSNAKTI
CDHLAVLRPHVWLMIGHCGGLRESQSIGDYVLAHAYLRDDHVLDAVLPPD
IPIPSIAEIQRALYDATKAVSGMPGVEVKQRLRTGTVVTSDDRNWELRFS
ASSLRFSLSRAVAVDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLP
GQANHFYEGAISEHLQIGIRAIDLIGGSSAKIRAMATRCRIPPDKSFGYR
VRNSLKPSVFSKSSTTDWHFSFDSPLMSMPNAIFFSTFIHGNSAYS
>YPO3123 apt, adenine phosphoribosyltransferase
MTVSASKTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIK
LLSEHYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETI
SESYELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLG
GEVVHAAFIINLPELGGEARLTQQGIHCYSLVSFDGH
>YPO0481 carA, carbamoyl-phosphate synthase small subunit
MIKSALLVLEDGTQFHGRAIGAEGTAVGEVVFNTSMTGYQEILTDPSYSR
QIVTLTYPHIGNVGTNASDEESSAVHAQGLVIRDLPLIASNYRNEEGLSE
YLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIVGELSDAALALEKAKAF
PGLKGMDLAKEVTTKEMYQWLQGSWTLEGDLPAAKQPEDLPFHVVAYDYG
VKRNILRMLVDRGCRLTVVPAQTPAEDVLKLNPDGIFLSNGPGDPEPCDY
AITAIKRFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDL
DASCVMITAQNHGFAVDETSLPSNLRTTHVSLFDGSLQGLHRTDKAAFSF
QGHPEASPGPHDAAPLFDHFIELIEAYRASSVSLNCSNSHK
>YPO0482 carB, carbamoyl-phosphate synthase large subunit
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSN
LATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCAL
ELERQGVLAEFGVTMIGATADAIDKAEDRRRFDIAMKKIGLDTARSGIAH
NMEEALAVAADVGFPCIIRPSFTMGGTGGGIAYNREEFEEICERGLDLSP
TKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITV
APAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFSVNPKNGRLIVIEM
NPRVSRSSALASKATGFPIAKIAAKLAVGYTLDELMNDITGGRTPASFEP
SIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALR
GLEVGATGFDPKVSLDDPEALTKIRRELKEAGAERIWYIADAFRAGMSVD
GVFNLTNVDRWFLVQIEELVRLEESVAELGINGLTAEFMRHLKRKGFADA
RLAKLVGAAESEVRKLRYKYGLHPVYKRVDTCAAEFSTDTAYMYSTYEEE
CESNPTSDRPKVMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVN
CNPETVSTDYDTSDRLYFESVTLEDVLEIVRIEKPQGVIVQYGGQTPLKL
ARELEAAGVPIIGTSPDAIDRAEDRERFQQAVNRLGLKQPANATVATIEQ
AVEKATGLGYPLVVRPSYVLGGRAMEIVYDEIDLRRYFQNAVSVSNDAPV
LLDRFLDDAVEVDVDAICDGERVLIGGIMEHIEQAGVHSGDSACSLPAYT
LSKEIQDVMRQQVEKLAFELCVRGLMNVQFAVKNNEVYLIEVNPRAARTV
PFVSKATGMPLAKIAARVMVGQSLAEQGMLEEIIPPYYSVKEVVLPFNKF
PGVDPILGPEMRSTGEVMGVGRTFAEAFSKAMLGSQSGMKKSGRALLSVR
EGDKHRVVDLAAKLLKQGFELDATHGTAVVLGEAGINPRLVNKVHEGRPH
IQDRIKNGEYTYIVNTTAGRQAIEDSKLIRRSALQYKVHYDTTLNGGFAT
AMALNADPTDQVISVQEMHAKIKNMKA
>YPO1512 cdd, cytidine deaminase
MQARFHTSWAELPASLQFALEPILSAENFPAMLTAEQVKTVKNISGLDDD
ALAFALLPLATACALTPISHFNVGAIARGKSGNFYFGANMEFRGVPLQQT
IHAEQCAVTHAWLRGETNLVAITVNYTPCGHCRQFMNELNSGSELHIHLP
GRPPSTLGQYLPDSFGPTDLAITTLLMDPVNHGYTLAETDPLTQAALNAA
NHSHAPYSQSHSGVALETTNGKIYAGRYAENAAFNPSLPPLQAALILANI
TGENCASIRRAVLVEGHNAVTSQWDTTLATLNALGCSAVKRVTF
>YPO1391 cmk, cytidylate kinase
MTAIAPVITVDGPSGAGKGTLCKALAESLNWRLLDSGAIYRVLALAALHH
QVDISTEEALVPLAAHLDVRFVSQNGQLQVILEGEDVSNEIRTETVGNTA
SQAAAFPRVREALLRRQRAFREAPGLIADGRDMGTIVFPDAPVKIFLDAS
SQERAHRRMLQLQERGFNVNFERLLAEIQERDNRDRNRSVAPLVPAADAL
VLDSTSMSIEQVIEQALAYAQRILALPLKK
>YPO0162 codA, cytosine deaminase
MEALMAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSL
TGQGVLDAQGGLALPPFIEPHIHLDTTQTAGQPSWNQSGTLFEGIERWAE
RKARLTREDVKQRAWQTLKWQIANGIQHVRTHVDVSDPHLTALSAMLEVK
EEVSPWVDMQIVAFPQEGILSYPDGAALLEEALRLGADAVGAIPHFEFTR
EYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVAALALRENMGA
RVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYP
KRRGITRVKEMLAAEINVCFGHDDVFDPWYPLGTANMLQVLHMGLHICQL
MGYEQINDGLNLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRR
QVPVSYSIRHGVVIAKTQPAESRIYLGQEEIVDFRR
>YPO3530 cpdB, 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein
MEKAMFKRPLTLSLLASLIAVATSLSAATVDLRVLETTDLHSNMMDFDYY
KDKPTEKFGLVRTASLIIAARQQATNSVLVDNGDVIQGSPLGDYIAAKGL
NDGEIHPVYKAMNTLDYAVGNIGNHEFNYGLDYLKKSLAGAKFPYVNANV
IDVKTGKPLFQPYLIIDTPVKDRDGKSHNLRIGYIGFVPPQVMIWDKANL
SGKVTVNDITETAKKWVPEMREQGADLVVAIPHSGLSSDPYKTMAENSVY
YLSQVPGIDAIMFGHAHGVFPSKDFAAIKGADITQGTLNGIPAVMPGQWG
DHLGVVDFVLNNDQGKWQVIDAKAEARPIYDKTAQKSLAAENAKLVEVLA
VDHQSTRDFVSQPIGKASDNMYSYLALIQDDPTVQIVNNAQRAYTEHFIQ
GDPDLADLPVLSAAAPFKAGGRKNDPTSFVEVEKGKLTFRNAADLYLYPN
TLVVVKASGAEVKQWLECSAAQFNQIDINSSKPQSLINWDGFRTYNFDVI
DGVEYEIDVSQPARYDGECTLINDQAERIKNLTFNGKPIDPKATFLIATN
NYRAYSGKFAGTGDSHIAFASPDENRAVLSAYISAETKKKGQVIPQADNN
WRLAILDSKQPLDIRFETSPTAKAADFIKQKAQYPMEAQGTDEVGFAVYH
IDLQRK
>YPO3848 cyaA, adenylate cyclase
MYLYIETLKQRLDAINQLRVDRALAAMGPAFQKVYSLLPILLHCHHPQMP
GYLDGNVPHGVCLFTPNEIQQDYLADVEARWGEPLAPSAGGELPITGVYS
MGSTSSIGQCHTSDLDIWVCHQAWLDTEERNQLQQKCSLLEKWAASMGVE
VSFFLVDENRFRHNASGSLGGEDCGSTQHILLLDEFYRSAVRLAGKRILW
NMVPVKEEEHYDDYVLSLYAQGVLTPNEWLDLGGLSTLSAEEYFGASLWQ
LYKSIDSPYKAVLKTLLLEAYSWEYPNSQLLAMEIKQHLHAGEIVSFGLD
AYCMMLDRVTRYLIQINDTTRLNLVRRCFYLKVCEKLSRTPASTGWRREV
LSQLVSEWGWSNEKLAVLDNRANWKIERVREAHNELLDAMMQSYRNLIRF
ARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEEHLT
FIHVPAGRANRPGWYLYNQAPSMDAIVSHQPLEYNRYLNKLVSWAYFNGL
LTSKTHLHIKSANLCDTVKLQELVTDISHHFPLRLAAPTPKALYSPCEIR
HLAIIVNLEHDPTTTFRNQVVHFDFRKLDVFSFGEQQQCLVGSIDLLYRN
SWNEVRTLHFSGEQAVLEALKTILGKMHQDAAPPESVDVFCYSQHLRGLI
RTRIQQLVSECIDLRLSSTRQEPGRFKAVRVSGQTWGLFFERLSVSVQKL
ENAVEFYGAISNNKLHGLSVQVETNQIHLPPVVDGFASEGIIQFFFEGTA
DEKGFNIYILDEANRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSF
INFNLPQFYQIVQLDGRTQVIPFRSNTLSQLCANIAEKEASLPTKQCQLH
>YPO1178 cyaB, adenylate cyclase 2
MSEHFVGKYEVELKFRVMDLTTLHEQLVAQKATAFTLNNHEKDIYLDANG
QDLADQQISMVLREMNPSGIRLWIVKGPGAERCEASNIEDVSKVQSMLAT
LGYHPAFTIEKQRSIYFVGKFHITVDHLTGLGDFAEIAIMTDDATELDKL
KAECRDFANTFGLQVDQQEPRSYRQLLGF
>YPO1525 dcd, deoxycytidine triphosphate deaminase
MRLCDRDIEAWLDSGKLGIEPRPPVERINGATVDVRLGNQFRVFRGHTAA
FIDLSGPKDEVSAALERVMSDEINLPEGEAFFLHPGELALAVTLESVTIP
DDLVGWLDGRSSLARLGLMVHVTAHRIDPGWQGRIVLEFYNSGKLPLALR
PGMLIGALSFEPLSGPAARPYNSRQDAKYRGQQGAVASRIDKD
>YPO0436 deoC, deoxyribose-phosphate aldolase
MTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTA
AICIYPRFIPVARKALREQGTPEIRIATVTNFPHGNDDVAIALAETRAAI
AYGADEVDVVFPYRALMAGNDKIGFELVKTCKEACAAANVLLKVIIETGE
LKQAHLIRQASEIAIKAGADFIKTSTGKVPVNATLESADIMIRTIRELGV
GETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWADARHFRFGASSLLASL
LTTLGHQSNANSSGY
>YPO0440 deoD, purine nucleoside phosphorylase
MATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFT
GTYKGRKISVMGHGMGIPSCSIYAKELITDFGVKKIIRVGSCGAVRTDVK
LRDVVIGMGACTDSKVNRMRFKDHDYAAIADFEMTRNAVDAAKAKGVNVR
VGNLFSADLFYTPDPQMFDVMEKYGILGVEMEAAGICGVAAEFGAKALTI
CTVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA
>YPO3383 dgt, deoxyguanosinetriphosphate triphosphohydrolase
MSGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQ
KTQVFPLERNAAVRSRLTHSLEVQQVGRYIAKEILNRFKQDKKITAYGLD
KLLDPFESIVEMACLMHDIGNPPFGHFGESAINDWFTKRMDPNGGSGSEP
QSTDQCQVDVLKLCEGETELNILRSKIRHDLSQFEGNAQAIRLVHSLLKL
NLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAEENYVKELRRE
LNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEW
GAVTPGDLFDKVVGAAFRQLGREQGRRSSEDQFFMYLRVNTVGKLVPHAA
QRFIENLPAVFSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQL
ELQGYRVISGLLDIYSPLLAMPETAFTQLVADDRHRKYPIETRLFHKLSI
KHRLAYAESAERIRNLPSEQYEIYEYYYRARLIQDYISGMTDLYAYDEYR
RLMAAE
>YPO0047 dut, deoxyuridine 5'-triphosphate nucleotidohydrolase
MKKIDIKILDPRVGNEFPLPTYATEGSAGLDLRACLDHAVELQPGQTTLL
PTGLAIHIGDSALAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSV
WNRGQQPFTIEPGERIAQMVFVPVVQAEFNLVEDFTDSERGTGGFGHSGR
Q
>YPO0040 gmk, guanylate kinase
MVQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENH
GEHYFFVSEKEFCQMIDDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVF
LDIDWQGAQQIRAKMPTARSIFILPPSKTELDRRLRGRGQDSEEVIAKRM
EQAVAEMAHYAEYDYLIVNDDFNLALSDLKTIIRAERLRLGRQKQRHDAL
ISKLLAD
>YPO3225 gpt, xanthine phosphoribosyltransferase
MNEKYVVTWDMLQIHARKLAQRLLPAEQWKGIIAVSRGGLVPAGILAREL
GIRYVDTVCISSYDHDNQRDLKVLKRAEGDGEGFIVIDDLVDTGGTATAI
REMYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMAVTFVAPLS
GK
>YPO2870 guaA, bifunctional GMP synthase/glutamine amidotransferase protein
MTKNIHKHRILILDFGSQYTQLLARRVREIGVYCELWAWDVTEAQIREFN
PSGIILSGSPESTIENGSPRAPDYVFTAGVPVLGVCYGMQTMAIQLGGKV
ESSNQREFGYAQVEIKADSALIRDIKDAINPAGEAVLDVWMSHGDKVAEI
PADFVTVASTDTCPFAIMANEEKRFYGVQFHPEVTHTKQGLRLLERFVLG
ICGCEALWTSATIIEDAIVRLREQIGDDHVILGLSGGVDSSVTAMLLHRA
IGKRLTCVFVDNGLLRLNEADQVLEMFGDKFGLNIVHVAAEDRFLSALTG
VDEPEAKRKIIGRVFVELFDEEACKQEQVKWLAQGTIYPDVIESAASATG
KAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTV
FLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRI
INEVNGISRVVYDISGKPPATIEWE
>YPO3428 guaC, guanosine 5'-monophosphate oxidoreductase
MRIEEGLKLGFKDVLIRPKRSTLKSRSEVALERQFTFKHSGWNWSGVPII
AANMDTVGTFRMAEVLASFDILTAVHKHYTLEQWAEFVKRSPESVLRHVM
VSTGTSSADFDKMKQILALSPSLKFICIDVANGYSEHFVSFLQRAREACP
DKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLS
AVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDE
CEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAQYRAAEGKTVKLPLRGS
VDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGTD
>YPO3408 hpt, hypoxanthine-guanine phosphoribosyltransferase
MRHTVEVMISEQEVKTRIAELGRQISEHYRDSGSDMVLVGLLRGSFMFMA
DLCRAIDVSHEVDFMTASSYGNGMSTTRDVKILKDLDEDIRGKDVLIVED
IIDSGNTLSKVREILQLRGPKSLAICTLLDKPERREVHVPVEWVGFTIPD
EFVVGYGIDYAQRYRHLPYVGKVVTLDE
>YPO3384 mtn, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
MKVGIIGAMEEEVTLLRDRIENRQTLARAGCEIYTGQLNGIDVALLKSGI
GKVAAAMGTTLLLEHCQPDLVINTGSAGGLDSSLKVGDIVVSNEVRYHDA
DVTAFGYEPGQMAGCPAAFVADEDLIALAENCIQQLKLNAVRGLICSGDA
FINGAEPLARIRAAFPTVAAVEMEAAAIGHVCYLFNTPFVVVRAISDVAD
QASHLSFEEFLVVAAKQSTLMIKAMLTTLAQRG
>YPO2883 ndk, nucleoside diphosphate kinase
MALERTFSIIKPNAVANNDIGAIYARFERAGFKIIAAKMLHLTKEQAEGF
YAEHKGRPFFDGLVEFMTSGPIMVQVLEGENAVQRHRDIMGATNPDNALA
GTLRADFSDSFTANAVHGSDAVESAQREIAYFFAADEIFPRS
>YPO1214 nrdA, ribonucleotide-diphosphate reductase alpha subunit
MNQSLLVTKRDGSKERINLDKIHRVIDWAAEGLHNVSVSQVELRSHIQFY
DGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPP
TLFAHVSKMVEMGKYDKHLLEDYTAEEFEQMDTFIDHWRDMNFSYAAVKQ
LEGKYLVQNRVSGEIYESAQFLYILVSACLFSGYPRETRLDYIKRFYDAI
STFKISLPTPIMAGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQ
RAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGG
AATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYQRLLKG
GDITLFSPSDVPGLYDAFFADQDEFERLYVKYEQDSSIRKQRVKAVELFS
LMMQERASTGRIYIQNVDHCNTHSPFDPKIAPVRQSNLCLEIALPTKPLN
DINDENGEIALCTLSAFNLGAIDSLDDLEDLAILAVRALDALLDYQDYPI
AAAQRGAMGRRTLGIGVINFAYYLAKNGVRYSDGSANNLTHRTFEAIQYY
LLKASNALAREQGACPWFNETTYSQGILPIDTYKKDLDAISNEPLHYDWE
TLRKEIQTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDG
ILRQVVPEYERLKGAYELLWEMPNNDGYLQLVGLMQKFVDQAISANTNYD
PTRFPSGKVPMKQLLKDLLTTYKFGVKTLYYQNTRDGADDVQEDIQSSLP
GDDDCEGGACKI
>YPO1213 nrdB, ribonucleotide-diphosphate reductase beta subunit
MAYTTFSQNKNNQLLEPMFFGQSVNVARFDQQKHAIFEKLIEKQLSFFWR
PEEIDVSRDRIDYNALPDHEKHIFISNLKYQTLLDSIQGRSPNVALLPLI
SIPELETWVETWSFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEEILKR
AKDISAYYDDLIEMTSYYHLLGEGTHQVNGKTVVVKLRDLKKQLYLCLMS
VNALEAIRFYVSFACSFAFAERELMEGNAKIIKMIARDEALHLTGTQHIL
NLMRLGEDDPEMAEIAEECQQQCYDLFVLAAQQEKEWAEYLFRDGSMIGL
NKEILCQYVEYITNIRMQAVGLGIPFSTRTNPIPWINSWLVSDNVQVAPQ
EVEVSSYLVGQIDSEVSADDLSDFEL
>YPO3454 nrdD, anaerobic ribonucleoside triphosphate reductase
MKTVVIKRDGCQVPFDEVRIKEAVERAALAVGVVDADYCATVARVVAQTM
ENQPKVDIREIQNAVENQLMAGQYKQLARAYIEYRHDRDISRELRGRLNQ
EIQGLVEQSNKALLNENANKDSKVIPTQRDLLAGIVAKHYAKQHLLPRDV
VLAHERGEIHYHDLDYAPFFPMFNCMLIDLEGMLTQGFKMGNAEIEPPKS
ISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESFNKHKAVAEEW
QIPDVAGYAMSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTS
WQSRMIQQAILRNRIAGLGKNRKTAVFPKLVFAIRDGLNHKFGDANYDIK
QLALECATKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVYEEEGQQIHD
GRNNLGVISLNLPRIALEAKGDENQFWQLLDERLLIAKKALMTRIARLEG
IKARVAPILYMEGACGVRLQADDNIAEIFKNGRASISLGYIGIHETINAL
FGHQTHLFDDQKLREKAIAIVAHLKQATDDWKDETGYAFSLYSTPSENLC
DRFCRLDTAEFGVVEGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPL
ANGGFICYGEYPNLQHNIRALEDVWDYSYSRVPYYGTNTPIDECYECGFT
GEFSCTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVK
RRVKHLANGQLG
>YPO2649 nrdE, ribonucleotide-diphosphate reductase alpha subunit
MLNLYDADGRIQFDKDRLAARQYFLQHVNQNTVFFHNLQEKIDYLIEEGY
YEKEVLDQYDFSFIKSLFQQAYSKKFRFPTFLGAFKYYTSYTLKTFDGKR
YLERYEDRVCMVALTLATGNQTLARELVEEIISGRFQPATPTFLNCGKKQ
RGELVSCFLLRIEDNMESIGRSINSALQLSKRGGGVAFLLSNIREVGAPI
KRIENQSSGVIPIMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLD
TKRENADEKVRIKTLSLGVVIPDITFELAKNNEEMYLFSPYDIEQVYGVP
MSEISISEKYREMVDNKRIRKSKIKAREFFQILAEIQFESGYPYMMFEDT
VNRANPIKGRINMSNLCSEILQVNAPTEYHEDLSYRRIGKDISCNLGSLN
IAQVMDSPDFGKSIEIAIRGLTAVSEMSNIRSVPSIEKGNQESHAIGLGQ
MNLHGYLARERLFYGSEEALDFTNIYFYTVAYHAIRASNQLAIERASHFK
GFDESDYASGAFFSKYIEQSWQPKTARVQALFADAGIAIPNQQDWIALRQ
SVMEHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSPIEIRKEGKIGRVY
YPAPYMTNDNLEYYQDAYQIGPEKIIDTYAAATQHVDQGLSLTLFFRDTA
TTRDINKAQIYAWKKGIKTIYYIRLRQMALEGTEVEGCVSCSL
>YPO2648 nrdF, ribonucleotide-diphosphate reductase beta subunit
MNVVKPITRISAINWNKIEDDKDLEVWNRLTSNFWLPEKVPLSNDIPSWA
TLTPHEQQLTIRVFTGLTLLDTIQNTLGAPALIKDAITPHEEAIFSNISF
MEAVHARSYSSIFSTLCLTSDVDDAYRWSEDNGPLQKKADIISQHYHNDD
PLKKKIASVFLESFLFYSGFYLPMYWSSRAKLTNTADLIRLIIRDEAVHG
YYIGYKFQKGLGKIDSAHRQEIKNFAFDLLQDLYDNEVRYTEDLYDHVGW
TEDVKKFLHYNANKALMNLGYEALFPASQAAVSPAILAALSPNADENHDF
FSGSGSSYVIGKAVNTEDEDWDF
>YPO2650 nrdI, hypothetical protein
MNPLVYFSSSSENSHRFVEKLQLPAIRIPIAGAREKLRVEQPYILLVPSY
GGGSPVGAVPIQVIRFLNDVHNRSLIRGVIAAGNTNFGDAYCLAGDIISH
KCQVPYLYRFELLGTAEDVANVRKGVTEFWQRQN
>YPO2983 nupC, nucleoside permease
MSHILQFALALVVVAILALAICKDRKSIRIRFVIQLLVIEVLLAYFFLHS
EAGLGFVKGFAGFFDTLLGFAAAGTDFVFNDMGDKGLAFFFLRVLCPIVF
ISALIGILQYIKVLPIVIRLIGTLLSKVNGMGKLESFNAVSSLILGQSEN
FIAYKDILGKMSEKRMYTMAATAMSTVSMSIVGAYMSMLDAKFVVAALVL
NMFSTFIVLSLINPYKVGEEQDLQLSNLHEGQSFFEMLGEYILAGFKVAI
IVAAMLIGFIALIAAVNALFTLLFGISFQGILGYVFFPFAWVMGIPAHEA
LQVGSIMATKLVSNEFVAMMDLQKVASQLSPRSVGILSVFLVSFANFSSI
GIVAGAIKGLNEHQGNVVSRFGLKLLYGSTLVSVLSASIAGLVL
>YPO2837 ppx, putative exopolyphosphatase
MPLTNNSTTKPQEIAAIDLGSNSFHMVIARVVNGALQVLGRLKQRVHLAD
GLDSNNMLSEEAIERGLACLALFAERLQGFSPDNVCIVGTHTLRQAANAE
TFLKRAAEVIPYPIEIISGQEEARLIFMGVEHTQPEKGRKLVIDIGGGST
EMVIGEDFEPLLVESRRMGCVSFAQQFFPGGEISKNNFRRARLAAAQKLE
NLAWQYRIQGWQYALGASGTIKATYEVLVEMGEKDGLITPERLEMLVENV
LQFKQFSALSLPGLSEDRQSVFVPGLAILCGVFDALAIKTLRLSDGALRE
GVLYEMEGRFRHQDIRQRTAKSLADHYNIDREQARRVLETTEQLYTQWLA
QNTKLVQPQLEALLKWAAMLHEVGLSINHSGMHRHSAYILQNTNLPGFNQ
EQQTLLATLVRMHRKAIKLDELPRLNLFKKKYYLPLIQLLRLSTLLNNQR
QSTTTPESLRLITDDSHWTLRFPHGYLTQNSLVQLDFEREQAYWDDVVGW
KLVIEEEEPDEAAKVAPEE
>YPO2013 prsA, ribose-phosphate pyrophosphokinase
MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRG
GDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRR
VRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSP
ILLEDMLQQNLENPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRAN
VSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATH
PIFSGNAVDNIRNSVIDEVIVCDTIPLSAEIKALKNVRTLTLSGMLAEAI
RRISNEESISAMFEH
>YPO0378 purA, adenylosuccinate synthetase
MGKNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEK
TVLHLIPSGILRENVISIIGNGVVLAPDALMKEMTELEARGVPVRERLLL
SEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVS
DLFNKETFAIKLKEIVEYHNFQLVHYYKEAAVDYQKVLDDVLAIADILTA
MVVDVSELLDNARKQGELIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVA
TGSGLGPRYVDYVLGIVKAYSTRVGAGPFPTELNDETGEFLRKQGNEYGA
TTGRSRRTGWLDIVAVRRAVQINSLSGFCMTKLDVLDGLKEVKLCVGYRM
PDGREVDTTPLAAEGWEGIEPIYETMPGWSETTFGVKEHSKLPQAALNYI
QRVEELTGVPIDIISTGPDRDETMILRDPFDA
>YPO1636 purB, adenylosuccinate lyase
MELSSLTAVSPIDGRYGDKVSALRPIFSEFGLLKFRVQVEVRWLQKLAAC
AEIKEVPAFDANANAYLDKIVQEFNEQDAQRIKTIERTTNHDVKAVEYFL
KEKVENLPALHAVSEFIHFACTSEDINNLSHALMLQTARQDVLLPAWRQI
IDSIKALAHQYRDLPLLSRTHGQPATPSTIGKELANVAYRMERQFRQLTQ
VEILGKINGAVGNYNAHIVAYPEVDWHQFSESFVTSLGINWNPYTTQIEP
HDYIAELFDCVARFNTILIDFDRDIWGYIALNHFKQKTIAGEIGSSTMPH
KVNPIDFENSEGNLGLSNAVLGHMASKLPVSRWQRDLTDSTVLRNLGVGL
GYALIAYQATMKGISKLEVNEAHLLQELDHNWEVLAEPIQTIMRRYGIEK
PYEKLKELTRGKRVDAAGMQAFIDGLDLPEEEKNRLKAMTPANYIGRATT
MVDELK
>YPO3059 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MQKLAELYRGKAKTVYTTENPDLLVLEFRNDTSALDGQRIEQFDRKGMVN
NKFNHFIMTKLEEAGIPTQMERLLSDTEVLVKKLEMIPVECVIRNRAAGS
LVKRLGIEEGLSLNPPLFDLFLKNDAMHDPMVNESYCKTFGWATEAQLAR
MKELSYLANDVLSKLFDDAGLILVDFKLEFGLFNGEVVLGDEFSPDGSRL
WDKKTLNKMDKDRYRQSLGGLIEAYEEVAHRIGVKLD
>YPO3729 purD, phosphoribosylamine--glycine ligase
MNILIIGNGGREHALGWKAAQSPLADKIYVAPGNAGTALEPTLENVDIAA
TDIAGLLAFAQSHDIGLTIVGPEAPLVIGVVDAFRAAGLAIFGPTQAAAQ
LEGSKAFTKDFLARHNIPSAEYQNFTDVEAALAYVRQKGAPIVIKADGLA
AGKGVIVAMTQEEAETAVNDMLAGNAFGDAGHRIVVEEFLDGEEASFIVM
VDGENVLPMATSQDHKRVGDGDTGPNTGGMGAYSPAPVVTDDVHQRVMDQ
VIWPTVRGMAAEGNIYTGFLYAGLMISADGQPKVIEFNCRFGDPETQPIM
LRMRSDLVELCLAGTQGKLNEKTSDWDERPSLGVVLAAGGYPADYRQGDV
IHGLPQQEVKDGKVFHAGTKLNGNHEVVTNGGRVLCVTALGETVAQAQQY
AYQLAEGIQWEGVFCRKDIGYRAIARGK
>YPO3076 purE, phosphoribosylaminoimidazole carboxylase catalytic subunit
MGANLNSAYAAGVKIAIVMGSKSDWATMQFAADVLTTLNVPFHVEVVSAH
RTPDRLFSFAEQAEANGLHVIIAGAGGAAHLPGMLAAKTLVPVLGVPVQS
AALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILALHDTELA
GRLAHWRQSQTDDVLDNPDPREEA
>YPO2772 purF, amidophosphoribosyltransferase
MCGIVGIAGFTPVNQSIYDALMVLQHRGQDAAGIVTIDAHNGFRLRKANG
LVKDVFETRHMLRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPFGITLA
HNGNLTNAHQLRKKLFEVSRRHVNTTSDSEILLNIFASELDRFQHYPLES
DNIFAAVAATHQLIRGAYACVAMIIGHGMVAFRDPNGIRPLVIGKRTLAD
GRNEYMVASESVALDTLDFEFLRDVAPGEAVYITEKGQLFTRQCAENPKY
NPCLFEYVYFARPDSFMDKISVYSARVRMGQKLGTKIAKQWEDMDIDVVI
PIPETSCDIALEIARILDKPYRQGFVKNRYVGRTFIMPGQQERRKSVRRK
LNANRAEFRGKNVLLVDDSIVRGTTSEQIVEMAREAGAKKVYFASAAPEI
RFPNVYGIDMPSANELIAHGREVDEIRQLIGADALIFQDLTDLIDAVRED
NPDITQFECSVFNGIYVTKDVDQSYLEYLESLRNDDAQALRSHNEAENLE
MHNEG
>YPO3728 purH, bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLP
VTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDI
VVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKS
SDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPP
YHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVA
TAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSI
LAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSS
DALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAAD
LRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSR
VYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPG
GSIRDDEVIAAADEHSIAMIFTDMRHFRH
>YPO2828 purI, phosphoribosylaminoimidazole synthetase
MTNKTSLSYKDAGVDIDAGNDLVDRIKGVVKQTRRPEVMGGLGGFGALCA
LPQKYREPILVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGA
EPLFFLDYFATGKLDVDTAASVITGIAEGCKQSGCALVGGETAEMPGMYH
GDDYDVAGFCVGVVEKSEIIDGSKVTPGDVLVALGASGPHSNGYSLVRKI
LDVSNTNPEQTSLEGKSLADHLLEPTKIYVKSILSLIEQLDIHAIAHLTG
GGFWENIPRVLPQGMQAVIDEASWQWPAVFSWLQQAGNVSRHEMYRTFNC
GVGMVVALPAELADKAVELLTASGEKAWKIGVIAAATEGAEQVIINP
>YPO3077 purK, phosphoribosylaminoimidazole carboxylase
MKPVCVLGNGQLGRMLRQAGEPLGIAVYPVGLDAEPEAVPYQHSVITAEI
ERWPETALTRELATHTAFVNRDIFPRLADRLPQKQLLDSLGLATAPWQLL
SSASEWPEVFATLGELAIVKRRVGGYDGRGQWRLRPGEQGTLPPDAYGEC
IVEQGINFSGEVSLIGARSHQGESVFYPLTHNLHEDGILRMSVALPQPNS
KLQQQAEKMLSAIMDKLNYVGVMAMECFIVGDRLLINELAPRVHNSGHWT
QNGASISQFELHLRAILDLPLPQPVVNTPSAMVNLIGTPVNIQWLSLPLV
HLHWYDKEVREGRKVGHLNLNDPEGTALSASLAALAPLLPAEYQNALRWA
QDKL
>YPO2921 purL, phosphoribosylformylglycinamidine synthase
MEILRGSPALSAFRITKLLSRCQDAHLLVSDIYAEYVHFADVSAPLSADE
HARLQRLLQYGPSLPEHPPAGRLLLVTPRPGTISPWSSKATDIAHNCGLS
QILRLERGLAFSIQGPDLNESQWKQLAALLHDRMMEAVFTDLQQAEQLFS
HHQPAPVQRVDILGQGRSALEQANIKLGLALAQDEIDYLLTAFTGLGRNP
TDIELYMFAQANSEHCRHKIFNADWVIDGVVQPKTLFKMIKNTFEHTPDY
VLSAYKDNAAVMEGSQVGRFYATAEKGIYDYHQEEAHILMKVETHNHPTA
ISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEE
NFGKPDRIVTALDIMTEGPLGGAAFNNEFGRPALLGYFRTYEERVNSHNG
IELRGYHKPIMLAGGLGNIRADHVQKGEITVGAKLVVLGGPSMNIGLGGG
AASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGEYNPILFIH
DVGAGGLSNAMPELVNDGGRGGRFELRDILNDEPGMSPLEVWCNESQERY
VLAVAPAQMALFDEICRRERAPYAVIGEATEEKHLLLNDRHFGNQPIDMP
LDVLLGKTPKMLRDVTRLQAKGDALQRADISLAEAVKRIMHLPAVAEKTF
LITIGDRTVTGMVTRDQMVGPWQIPVADCAVTSASLDSYYGEAMSLGERA
PVALLDFAASARLAVGEALTNIAATQIGELKRIKLSANWMSAAGHPGEDA
GLYDAVRAVGEELCPALEITIPVGKDSMSMKTRWQEGHEQREMTSPLSLV
ITAFARIEDVRRTVTPQLRTDKGDNALLLIDLGAGHNALGATALTQVYRQ
LGDKPADVRNVQQLAGFFNAMQRLVADQHLLAYHDRSDGGLLVTLAEMAF
AGHCGVTVDIQSLGNDALAALFNEELGAVIQVRAEQRADVEKLLADHGLA
NCVHYLGRAVAGDTFDIRSGTDVVYSEKRSTLRLWWAETSWQMQRLRDNP
DCADQEHQAKQDESDPGLNVKLTFDPAEDIAAPFILKQARPKVAVLREQG
VNSHVEMAAAFHRAGFDAVDVHMSDLLAGRTDLQSFQTLVACGGFSYGDV
LGAGEGWAKSILFNDRVRDEFEAFFHRPTTLALGVCNGCQMMSNLRELIP
GAEHWPRFVRNLSDSFEARFSLVEVASSPSLFMQDMVGSRMPIAVSHGEG
QVEVRDAAHLAALEQSHLVALRFVNNHGVVTEQYPANPNGSANGITAVTS
VSGRATVMMPHPERVFRTVSNSWHPEEWGEDSPWMRMFRNARKQLG
>YPO2829 purN, phosphoribosylglycinamide formyltransferase
MKKIVVLISGQGSNLQALIDAQQQGRISGKISAVFSNNPAAYGLERAESA
GIPHHALDAKAFTDRVSFDLALAQAIDQYQPDLLVLAGYMRILSPEFVKH
YAGRMLNIHPSLLPKYPGLHTHRQALENGDQEHGTSVHFVTEELDGGPVI
LQAKVPIFSDDSEEDVAERVQTQEHSIYPLVVSWFTDGRLAMRDNAAWLD
GVRLPLQGYAAE
>YPO1775 purT, 5'-phosphoribosylglycinamide transformylase
MLTIGTALRPGATRVMLLGAGELGKEVAIECQRLGLEVIAVDRYADAPAM
HVAHRSHVINMLDGAALKQLVAQEKPHYIVPEIEAIATDMLVELEKMGQH
VVPCAEATRLTMNREGIRRLAAETLQLPTSSYRFADTDSAFFQAVRDIGY
PCIVKPVMSSSGKGQSLIRSEEHLQAAWEYAQQGGRAGSGRVIIEGLVHF
DFEITLLTIRAVDGIHFCAPIGHRQEDGDYRESWQPQAMSDIALQRAKEI
SAQVVTALGGFGLFGVELFVCGDDVIFSEVSPRPHDTGMVTLISQNMSEF
ALHVRAFLGLPIGTIRQYGAAASAVILPELTSQNITYRGLETALIGDTQI
RLFGKPEIAGKRRLGVALAVADNIETAIEVAKKAAGNIEVSGE
>YPO3588 pyrB, aspartate carbamoyltransferase catalytic subunit
MANPLYHKHIISINDLSRDELELVLRTAASLKKTPQPELLKHKVIASCFF
EASTRTRLSFETSIHRLGASVVGFSDSSNTSLGKKGETLADTMSVISTYV
DAIVMRHPQEGASRLAAQFSGNVPIVNAGDGANQHPTQTLLDLFTIQETQ
GRLDNINIAMVGDLKYGRTVHSLTQALAKFNGNHFFFIAPDALAMPAYIL
QMLEEKEIEYSLHESLEEVVPELDILYMTRVQKERLDPSEYANVKAQFIL
RSSDLTGARDNLKVLHPLPRIDEITTDVDKTPYAYYFQQAGNGIFARQAL
LALVLNAELAL
>YPO1587 pyrC, dihydroorotase
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPI
TTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFT
AAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDI
FDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVT
PQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGT
DSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNG
PRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
>YPO1415 pyrD, dihydroorotate dehydrogenase
MYYPLVRKALFQLDPERAHELTFRQLKRVSGTPLEFLVRQSVPTKPVSCM
GLSFKNPVGLAAGLDKDGECIDALGAMGFGFIEVGTVTPRPQVGNDKPRL
FRIVEAEGLINRMGFNNHGVDNLIENVKKSHFGGILGINIGKNKDTPVEQ
GKEDYLICMDKIYPYAGYIAINISSPNTPGLRSLQYGEALDDLLAAIKDK
QTELHQRHHKYVPVAVKIAPDLTEEELIQIADSLVRHNIDGVIATNTTLD
RSLIQGLNYCEQAGGLSGRPLQLRSTEVIHRLSQELKGRLPIIGVGGIDS
VTAAREKMAAGASLIQIYSGFIFRGPGLIKNIVTHI
>YPO0045 pyrE, orotate phosphoribosyltransferase
MKAYQREFIEFALNKQVLKFGEFTLKSGRISPYFFNAGLFNTGLDLAKLG
RFYAAALMDCGVEFDLLFGPAYKGIPIATTTAVALAEHHERDVPYCFNRK
EAKTHGEGGNLVGSPLQGRVMLVDDVITAGTAIRESMEIINAQGATLAGV
MISLDRQERGRGEISAIQEVERDYHCKVIAIVTLNDVIRYLEDKPEMAEH
LVAVRQYREQYGVTL
>YPO2227 pyrF, orotidine 5'-phosphate decarboxylase
MTSATKTNNSGSISSPIVVALDYANKDAALAFADQVSPQDCRLKVGKEMF
TLYGPELIRDLHQRGFDVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHA
SGGARMMSAAKEALLPYGAQAPLLIAVTVLTSMDGEDLRDIGITISPAEQ
AERLAKLTWDCGLDGVVCSAHEAVRLKQVCGEDFSLVTPGIRPQGSEAGD
QRRIMTPEQAVAVGVDYMVIGRPITQSPDPEKTLREILASLTKVA
>YPO3377 pyrG, CTP synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPG
TMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTRRNNFTTGRIYSEVL
RKERRGDYLGATIQVIPHITNAIKERIIEGGEGHDVVLVEIGGTVGDIES
LPFLEAIRQMAVDVGREHTLYMHLTLVPYLAAAGEVKTKPTQHSVKELLS
IGIQPDVLICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGL
LKSQGLDDYICKRFSLTCPEANLAEWEQVLYEESNPGGEVTIGMIGKYVE
LPDAYKSVIEALKHGGLKNRLTVNIKLIDSQDVETRGEEMLKELDAILIP
GGFGYRGVEGKVLAARYAREHNIPYLGICLGMQVALMEFARNVAGMENAN
STEFVPDCKYPVVALITEWRDEDGNVEIRTEESDLGGTMRVGGQQCHLTE
GSLVRQMYGEPTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSADNKLVEI
IELPDHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAGDYQKRQVK
>YPO1046 pyrH, uridylate kinase
MATNAKPVYQRILLKLSGEALQGAEGFGIDASVLDRMAQEVKELVELGIQ
VGVVIGGGNLFRGAGLAQAGMNRVVGDHMGMLATVMNGLAMRDALHRAYV
NARLMSAIPLNGVCDNYSWAEAISLLRHNRVVIFAAGTGNPFFTTDSAAC
LRGIEIEADVVLKATKVDGVYSADPVKNPDATLYEQLTYQDVLEQELKVM
DLAAFTLARDHNLPIRVFNMNKPGALRRVVMGENEGTLIAK
>YPO3589 pyrI, aspartate carbamoyltransferase regulatory subunit
MTQDYKLQVEAIKCGTVIDHIPAQIGFKLLSLFKLTATDQRITIGLNLPS
KRSGRKDLIKIENTFLTEQQANQLAMYAPDATVNRIDNYEVVKKLTLSLP
ERIDAVLTCPNSNCISHNEPVDSSFTVKAQRGEISLKCKYCEKEFDHLTV
LHAD
>YPO2176 tdk, thymidine kinase
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTLVFTAEIDNRFGVGTVS
SRIGLSSQAQLYNSGTSLLSIIAAEHQDTPIHCILLDECQFLTKEQVQEL
CQVVDELHLPVLCYGLRTDFLGELFPGSKYLLAWADKLVELKTICHCGRK
ANMVLRLDEQGRAVHNGEQVVIGGNESYVSVCRRHYKEAIKAACCS
>YPO0783 thyA, thymidylate synthase
MKQYLDLMKKVLEEGTPKADRTGTGTLSIFGHQMRFNLQDGFPLVTTKRC
HLRSIIHELLWFLNGDTNIAYLKENNVSIWDEWADENGDLGPIYGKQWRA
WGAADGRKIDQLSNVVNQLKQDPDSRRIIVSAWNVGELDQMALAPCHAFF
QFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLAVGDFV
WTGGDTHLYSNHIDQAHLQLSREPRVLPKLVIKRKPDSLFDYHFDDFDIE
GYDPHPGIKAPIAI
>YPO1605 tmk, thymidylate kinase
MNSKFIVIEGLEGAGKTTTRDTVVAVLRAQGINDIVFTREPGGTPLAEKL
RDLIKQGIDGEVLTDKAEVLMLYAARVQLVENVIKPALARGSWVVGDRHD
LSSQAYQGGGRGIDSQLMASLRDTVLGEFRPDLTLYLDLPPAVGLARARA
RGELDRIEQESLAFFERTRARYLELAASDASIKTIDASQPIEQVSASISQ
ALAQWLTNQEPV
>YPO1524 udk, uridine kinase
MTDKAHQCVIIGIAGASASGKSLIASTLYRELREQVGDQHIGVIPEDGYY
KDQSHLSMEERVKTNYDHPSAMDHNLLLEHLQALKAGKPVELPLYSYTEH
TRKKETVHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRM
KRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIA
IDILKAKISQFFE
>YPO3786 udp, uridine phosphorylase
MAKSDVFHLGLTKNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREF
TSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVRTFLRIGTTGAIQP
HINVGDVLVTTAAVRLDGASLHFAPMEFPAVADFSCTTALVNAAKSVGAT
THIGITASSDTFYPGQERYDTFSGRVVRHFKGSMEEWQSMGVMNYEMESA
TLLTMCASQGLRAGMVAGVIVNRTQQEIPNEETMKATESHAVKIVVEAAR
HLL
>YPO2827 upp, uracil phosphoribosyltransferase
MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYVATADLETE
TVTIEGWNGPVEIEQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVG
VYRDEETLKPVPYFQKLVSNINERMALVVDPMLATGGSMIATIDLLKKAG
CQSIKVLVLVAAPEGIKALEEAHPDVELYTASIDQGLNEHGYIIPGLGDA
GDKIFGTK
>YPO1171 xapA, purine nucleoside phosphorylase
MTTVNSNINVDADFNELPFQAVKYIQKIKPGFKPQIAFILGSGLGDLVDQ
ITNDTTISYADIPGFPVSSVHGHAGELVLGDLCGVPVMCMKGRGHFYEGK
GMSIMTNPVRTFKLMGCEFLFCTNAAGSLRPEVLPGSVVMLKDHINTMPG
TPLVGPNDDRFGPRFFSLANAYDKDLRADMAKIAQQLDIPLTEGVFVSYL
GPCFETPAEIRMMQIIGGDVVGMSVVPEVLSAAHCGLKVIALTAITNLAE
GLSDVVLSHEQTLKFAKVASVNFTKLIEAFLKSKALR